Membrane glycoprotein thought to bind IGF-2. Defective in Simpson-Golabi-Behmel syndrome.

Dictionary of molecular biology. 2004.

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  • Simpson-Golabi-Behmel syndrome — (= SGBS) Human disorder leading to overgrowth. Arises through mutation in glycipan 3 gene on X chromosome probably reducing the extent to which IGF 2 is bound and unavailable for growth stimulation …   Dictionary of molecular biology

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